Injectable Liquid Vial Filling Machine

Automatic High Speed Injectable Powder Filling with Rubber Stoppering Machine

Model No.: SBPF-250D


Automatic High Speed Injectable Powder Filling with Rubber Stoppering Machine is a Double Wheel Double Track Powder Filling Machine with Vibratory Rubber Stoppering Unit to feed higher quantity of rubber stopper to the feeding chute for High Speed Performance of Machine.

The incoming dry vials (sterilized and siliconised) are fed through the unscrambler with suitably guided on the moving delrin flat conveyor belt at the required speed of the correct placement below powder wheel.

The sterilized powder stored in two powder hoppers is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density, each powder wheel having eight ports rotates at the pre determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel, vacuum plate is provided there is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked in to the port of powder wheel during vacuum according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade, the doctor blades can also be adjusted from outside without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the vial. The time dose of Compressed air, sterilized low pressure air or Nitrogen Gas sequentially flushes out powder from the port of powder wheel in to the container one by one. It is a double wheel Double track machine, so each powder wheel is filling vials alternately with double track system. The filled vials are immediately separated on the conveyor by vial separator and moves further for stoppering operation. (Different grooves separator can be used which depends on the container diameter or multiple dosing system.) After separated from vial separator, vials move further towards rubber stoppering unit and in between it will be converted in to single track from from double track with the help of suitable guide rails on machine conveyor.

The sterilized and siliconised rubber stoppers stored in the vibrator bowl moves vertically to the rubber stopper chute. The vial is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further the vials are passed between two pressing roller for tight fit fixing of rubber stopper. After stoppering operation, vials will be collected in to the Scrambler and move towards sealing machine for Vial sealing operation.

Technical Specification of High Speed Injectable Powder Filling Machine

Model SBPF-250D
Direction Left To Right
Production Rate. Up to 240 fills / Min for Single Dose.
Up to 120 fills / Min for Double Dose.
Up to 80 fills / Min for Triple Dose.
Up to 60 fills / Min for Four Dose.
Fill Capacity 50 mg 1.5 grms. Single Dose (with Change Parts) 1.5 grms to 6 grms. Double, Triple and Four Dose. Fill range depending upon vial opening and bulk density of powder.
Accuracy ± 1% depending upon consistency and the uniformity of bulk density of injectable powder Under controlled level of Humidity (i.e. 25%)
Electrical Supply 1.00 HP For Main Drive
0.50 HP For Unscrambler
0.50 HP For Scrambler
Power Requirement 440 Volts, 3 Phase (4 wire System) 50 Hz.
Height of Conveyor Adjustable from 800 to 850 mm
Diamensions 3759 mm (L) x 1242 mm (W) x 1885 mm (H)
Net Wight 1050 KGS. (Approx.)
Gross Weight 1550 KGS. (Approx.)

Input Specifications

Vial Diameter 25 mm to 38 mm Max.
Height 75 mm Maximum.
Rubber Stopper 20 mm Diameter.

(1) Right of technical improvements & modifications reserved

(2) All illustrations and dimensions are shown for information only

Salient Features

  • M.S. Moulded structure duly powder coated to avoid any vibration, with adjustable screws to adjust conveyor height as per infeed tunnel.

  • Total cGMP model.

  • All parts and assemblies coming in contact with powder and rubber stopper are made of S.S.316 and easily removable for mandatory Autoclaving / Sterilisation.

  • 'NO VIAL, NO FILL' System eliminates wastage of costly powder.

  • Spring loaded Teflon top seal for powder hopper reduces the friction between and top seal and avoid chance of white particle shading during production.

  • Doctor blade and wiper blade can be adjusted from outside also without disturbing any production, which saves lot of time, powder wastage and chances of area condition disturbance.

  • All assemblies under top plate are positioned as for easy cleaning or maintenance.

  • Multiple dosing of injectable powder or change over of vial size and different fill size is possible by just changing the vial separator or size of the piston respectively.

  • All driving is without High quality imported Gear motor for better machine performance without vibration or leakage of oil in area floor gear box.

  • Machine speed can be adjusted through A.C. Frequency drive, which is time saving and easy to synchronise unscrambler and scrambler speed with machine speed.

  • Machine is provided with delrin conveyor belt to avoid sticking of vial on conveyor.

  • Special clutch devices are provided on vial separator for safety purpose.

  • Vibratory bowl for rubber stoppering unit support to run machine with total claimed speed of machine.

  • Air filter will be of S.S.316 housing with Nylon cartridge for proper removal of particle of 0.22 micron having 10 ' length.

  • Vacuum filter will be of PVC transparent material with nylon cartridge having length of 10'.

Utilities (To be Provided by Buyer)

Pneumatic Air : Filtered, oil free, sterile low pressure AIR at 4 kg/cm2 (4/6 bar)

Vacuum line : 20 HG. (Pump will be supplied by S.B)

Basic Machine

  • Imported Gear Motor for Main drive, Unscrambler and scrambler.

  • A.C. Frequency drive for Main drive, Unscrambler and Scrambler.

  • Pre and Post Gasing unit for Nitrogen or Carbon Dioxide flushing.

  • Pure air filter for Air and Vacuum.

  • 'No Vial, No Filling' System.

  • 'No Stopper In Chute, Machine Stop System'.

  • Vacuum pump.

  • Acrylic Cabinet with Imported Aluminum Structure for Machine, Unscrambler and Scrambler.

Video – Injectable Powder Filling Machine