Prefilled Syringe Filling Machine

Suppository Production Line

Suppository Production Line

Suppository Filling Line Instruction and description

  • Operating principle: Suppository Filling and Sealing Machine

    • Finalize the design: Use PVC/PE through clamp structure and pass into molding district to preheat mould making shape mould air filling mould membrane making shape. Triangle knife side cut,dotted line cutting.

    • Filling part: There are 3-6 filling terminal,with embedded type filling for shaped suppository for one time, filling accuracy can get ±1%,there is electrical heating system to keep heat for raw material barrel, and there is mixing motor for raw material, the raw material of charging basket entrance into filling terminal through circulator, and the rest raw material circulate to the barrel for next filling.

    • Cooling part: Whole row is finished filling and passed into cooling shelf, cooling box is set cooling water unit, and cooling air is transformed by four condensers which is into the cooler bin to cool suppository.

    • Seal and print code part: Cooled solid suppository is sent to the seal district: preheat mould——>seal mould——>code print mould. And finished product is cut for 5 grains or 6 grains for a group.(according to customer’s requirement)

  • Main parts induction: Suppository Machine

    • Molding filling part: It is formed by film plate、transmit clamp、molding、finishing base、dotted line cutting、filling pump、material barrel、material circulator and section cutting, finish film making shell, material filling process.

      Molding filling part

    • Molding: Package material from film place plate through guide wheel and transmit tongs entrance into shaping processing, there are preheat , heat and shaping mould, and slot is loaded butt joint model (gassing mould) for production.

      Shaping diagram

      Base finishing and dotted line cutting base: Film material after shaping with cutter processing bottom margin, dotted line cutting

      Processing bottom margin

      Dotted line cutting

    • Filling: It is formed by filling pump, material barrel, stirrer, Circulation pump, to finish filling process.Filling pump have several plunger pump, adjust filling quantity by hand shank on the top of it, there is 6 or 7 terminals injector at the lower part of pump.Add the material into material barrel, heat the element to keep certain temperature, and mixer is driver by speed motor, keep the uniformity temperature, circulator keep material is cycled between material barrel and filling pump.

      Material barrel, Mixer and circulator

    • Segmentation and cutting: According to setting , the film material is cut 30 grain per row or 28 grain per row.

      Segmentation and cutting

    • Cooler bin parts: It is formed by two cooling tunnels and air coolers, to finish solidify process.segmented strip entrance cooling tunnel and cool, circulator repeat running send it to suppository sealing process water chiller supply cool water, which is homodisperse by cooling fan,and the temperature is controlled 8℃~16℃.

      Cooler bin

      Cooling tunnel

    • Finish sealing trail part: solidified strips are reheated after suppository sealing, and printed lot number.

Specification and Main Parameters of Suppository Filling & Sealing Machine:

Model Unit Suppository filling and sealing machine
Capacity PCS/Hour 8000-12000 (depending on producing)
Total Power KW 7.5Kw
Voltage, frequency V 3PH 380 +/-10% 50Hz
Dose per unit ML 0.5~5 (depending on product)
Deviation % <±2
Suppository shape N/A Bullet, torpedo, duck-mouth ect (depending on product)
Adapting N/A Fatty acid glycerin,gelatin,glycol,etc., (depending on product)
Volume L 50
Air pressure Mpa 0.6
Air consumption m3 1.5
Water consumption N/A 50kg per circle
Total weight KG 2000 - Approx
Machine dimensions MM 3100*3480*2000mm - Approx

Item Name remark
Shaping part Film placed plate(mating 2 brake cylinder)  

pneumatic element is from AirTac
Film guide

Clamp film running device(mating 1 cylinder)
Molding device(mating 3 pair cylinder)
Pushing calibrator(mating 1 cylinder)
Gassing device(mating 1 air-vent valve )
thimble(mating 1 cylinder)
Shaping part box(include internal holder) Raw material:aluminum、 stainless steel
Filling part dotted line knife(mating 1 pair cylinder)  

pneumatic element is from Airtac
triangular knife(mating 1 cylinder)
Filling device(pneumatic)
Filling terminal(mating different specification as needed )
charging basket(mixing motor)
charging basket circulator(mating 1 cylinder )
Filling part box(include internal holder) Raw material:aluminum、 stainless steel
Organic glass shield  

Cooling part Cool water

Famous brand compressor
Air cool

Strips step-by-step system(pneumatic) pneumatic element

Cooling part box(include internal holder) Raw material:aluminum、 stainless steel
Organic glass shield  

Sealing part Sealing reheat device


pneumatic element is from Mindman
Heat seal device

date of manufacture steel seal(mating 3 pairs cylinder)
Cutting hob

Strip tailor device

Sealing part box(include internal holder) Raw material:aluminum、 stainless steel
Organic glass shield  

Elctrcal contolling system PLC communication module

human-computer interface



thermoregulator, Suppository Thermoforming Machine


Electromagnetic valve air processing AirTAC
optoelectronic switch / approach switch / limit switch


warning device


Free spare parts with Suppository Machines

Name Quantity
Suppository mould 1Set
Resistance heating rods 1Set
Air-joint 1Set
Dotted cutter 5Sets
Sealing ring 1Set


  • PLC checking function: through PLC online checking function to self-checking and alarm for running stoppage, and show the reason of stoppage in order that the operator remedy it in time.

  • Suppository Filling part within free static electricity system.

  • Agitation vat speed adjustment system

  • Cooling speed adjustment system

  • Cutting gains speed adjustment system

  • Notice: finished products can be set 4/5/6/7pcs. The machine can product PVC/PE

  • Meet cGMP

Suppository Production Line Video